余长俊,男,汉族,1993年生,甘肃兰州人。2023年博士毕业于兰州大学生物化学与分子生物学专业,获理学博士学位,现为bwin必赢讲师。主要的研究方向为创新多肽药物的发现与改造,药物研发导向的功能有机分子化合物库的构建。先后参与完成国家自然科学基金项目,中国医学科学院医学与健康科技创新工程等项目的研究,迄今在Angew. Chem. Int. Ed.、ChemMedChem等国际学术期刊上发表SCI论文6篇,申请国家发明专利1项。
代表性论文
1. Changjun Yu, Ruiyao E., Xiao-Wei Zhang, Wen-Qian Hu, Guangjun Bao, Yiping Li, Yuyang Liu, Zeyuan He, Jingyue Li, Wen Ma, Ling-Yun Mou*, Rui Wang*, Wangsheng Sun*. NaClO-Mediated Cross Installation of Indoles and Azoles Benefits Anticancer Hit Discovery. ChemMedChem., 2023, 18, e202200651.
2. Ming Zhang+, Changjun Yu+, Junqiu Xie+, Xudong, Xun, Wangsheng Sun*, Liang Hong*, Rui Wang*. Phosphoric Acid Catalyzed Asymmetric [2+2] Cyclization/Penicillin–Penillonic Acid Rearrangement. Angew. Chem. Int. Ed., 2018, 57, 4921–4925. (共同第一作者)
3. Yiping Li, Jingyue Li, Guangjun Bao, Changjun Yu, Yuyang Liu, Zeyuan He, Peng Wang, Wen Ma, Junqiu Xie, Wangsheng Sun*, Rui Wang*. NDTP Mediated Direct Rapid Amide and Peptide Synthesis without Epimerization. Org. Lett., 2022, 24, 1169−1174.
4. Yuyang Liu+, Zeyuan He+, Wen Ma, Guangjun Bao, Yiping Li, Changjun Yu, Jingyue Li, Ruiyao E., Zhaoqing Xu*, Rui Wang*, Wangsheng Sun*. Copper(I)-Catalyzed Late-Stage Introduction of Oxime Ethers into Peptides at the Carboxylic Acid Site. Org. Lett., 2022, 24, 9248−9253.
5. Guangjun Bao+, Peng Wang+, Guofeng Li+, Changjun Yu, Yiping Li, Yuyang Liu, Zeyuan He, Tiantian Zhao, Jing Rao, Junqiu Xie, Liang Hong, Wangsheng Sun,* Rui Wang*. 1,3-Dipolar Cycloaddition between Dehydroalanines and C,N-Cyclic Azomethine Imines: Application to Late-Stage Peptide Modification. Angew.Chem. Int. Ed., 2021, 60, 5331-5338.
6. Junxian Yang, Wangsheng Sun*, Zeyuan He, Changjun Yu, Guangjun Bao, Yiping Li, Yuyang Liu, Liang Hong*, Rui Wang*. Access to α,γ-Diamino Diacid Derivatives via Organocatalytic Asymmetric 1,4-Addition of Azlactones and Dehydroalanines. Org. Lett., 2018, 20, 7080−7084.
授权专利
1. 孙旺盛;王锐;余长俊;鄂睿尧;牟凌云;张晓玮,吲哚联氮杂环化合物及其合成方法和应用,国家发明专利,202210380012.6
联系方式
通讯地址:bwin必赢(兰州市七里河区彭家坪路36号)
邮编:730050
邮箱:yucj@lut.edu.cn